Research Laboratory Technologist

Department BSD NEU - Mastrianni Lab About the Department The Department of Neurology at The University of Chicago Medical Center has a great history and tradition, having made significant contributions to neurological training, clinical care, and the basic understanding of neurological disease. Job Summary The Research Laboratory Technologist is a part-time position to support research and bench work laboratory studies of prion disease and Alzheimer’s Disease. Research studies are focused on microbiome research across cultures, and studies to monitor agitation in patients more accurately using wearable devices. Bench studies involve supporting research being done on prion diseases and Alzheimer’s Disease. Goals of the studies are primarily focused on the nature of prion disease pathology and the development of therapies, such as RNAi, gene splicing modification, and dominant-negative inhibition of disease in animal models of prion disease. The Mastrianni Lab. https://voices.uchicago.edu/mastriannilab/ Responsibilities Handling small rodents (mice and hamsters), PCR genotyping to maintain several transgenic mouse lines. Performing western blots, real time RT-PCR, cloning, restriction enzyme digestion, sequencing of human DNA samples, cell cultures, cell transfections. Maintain a laboratory database and perform routine laboratory maintenance (ordering supplies, etc.). Guide participants in such studies, packaging and mailing kits to patients for recovery of biological samples (microbiome), and assisting with a study that uses a wearable device to monitor agitation in patients with dementia. Maintains technical and administrative support for a research project. Analyzes and maintains data and/or specimens. Conducts literature reviews. Assists with preparation of reports, manuscripts and other documents. Performs other related work as needed. Minimum Qualifications Education: Minimum requirements include a college or university degree in related field. Work Experience: Minimum requirements include knowledge and skills developed through